Human Papillomavirus (HPV) is the leading cause of cervical cancer, with types 16 and 18 responsible for about 70% of cases worldwide C. Uganda introduced HPV vaccination in 2014, targeting 10-year-old girls with a two-dose schedule C. Recent efforts by the Ministry of Health and partners have scaled up vaccination campaigns, especially in underserved districts D. Vaccination is a powerful tool to reduce future cervical cancer cases, and community sensitization ensures parents understand its importance. In Kamuli, promoting HPV vaccination among adolescents is a cornerstone of prevention.